Note: The Nylon profiles have been developed for the Ultimaker 2+, Ultimaker 2 Extended+, Ultimaker 3, and Ultimaker 3 Extended and therefore the instructions on this page focus on these printers. You can try this material on other Ultimakers, but it is not supported.
Nylon is a highly durable printing material with a lot of great uses, particularly for functional prototypes of end-use parts. It has a high strength-to-weight ratio, is fairly flexible, resistant to corrosion, and can withstand fairly heavy use. It's best suited to make tools and other used parts. If you're printing decorative non-functional models, your best filament choice is PLA, for it's ease of use and high quality.
One thing to be aware of us that nylon does have a fairly significant shrinkage rate, so in order to improve adhesion, we strongly recommend helping control the ambient temperature by enclosing the machine if possible, and turning on the brim feature on models that may be likely to lift. Irregular shapes--like something U shaped, or gear shaped--are going to be more likely to suffer adhesion issues than a solid circle or square. So for example, with a bottom layer that looks like this, I'd recommend turning on brim.
We also recommend using a layer of glue to help improve adhesion on prints that don't require brim.
While having the fans on to some extent with nylon is helpful for the cooling process, you do not want to increase the fan speed to more than 60%, or you'll be introducing too much cooling.
The raptor reloaded e-nable hand I started printing has a lot of flexibility and strength. However, due to the U-shape of the print, the front sides came up off the bed during my first few tries at printing this, with the edges lifting off the bed as it cooled. For a successful print, I found this shape in this material really needed to have the brim turned on under the Adhesion settings.
The default printing temperature for nylon is 260 C, with a 60 C bed, though you can also turn it up to 70 C if 60 C isn't quite giving you enough heat.